HOpe for contrast-induced acute kidney injury.
editorial · Level V
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- Record sourced from PubMed, PMID 17914415.
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Abstract
Contrast-induced nephropathy (CIN) is a common cause of acute kidney injury in hospitalized patients. The mechanisms involved in the pathogenesis of CIN are incompletely understood. Goodman et al. have demonstrated for the first time that heme oxygenase-1, a 32-kilodalton protein with antioxidant, antiapoptotic, anti-inflammatory effects, is induced in the kidney and, importantly, provides a beneficial effect in CIN.
Medical subject headings
- Acute Kidney Injury
- Contrast Media
- Heme Oxygenase-1