Not so fast: adaptive suppression of innate immunity.

Palm, Noah W; Medzhitov, Ruslan · Nat Med · 2007

editorial · Level V

Where this comes from

Abstract

The innate and adaptive immune systems act in concert to effectively combat infection while minimizing collater al damage caused by the host immune response. T cells of the adaptive immune system have now been shown to suppress overzealous early innate responses to infection that can lead to 'cytokine storm'–mediated death (pages 1248–1252).

Medical subject headings