Loss of T-bet sends host-microbe mutualism awry.
editorial · Level V
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Abstract
Immune homeostasis in the intestine involves complex interactions between microbial organisms and host cells. In this issue, Garrett et al. (2007) describe a communicable form of colitis that is induced by deficiency of the transcription factor T-bet in cells of the innate immune system.
Medical subject headings
- Colitis, Ulcerative
- Homeostasis
- Immunity, Innate
- Intestines
- T-Box Domain Proteins