Penetration of antibiotics through omiderm in vitro and on split-thickness skin grafts in burn patients.

Russavage, J M; Slater, H; Goldfarb, I W; Hammell, E J · Ann Plast Surg · 1991

prospective_cohort · Level II

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Abstract

Penetration of antibiotic preparations (gentamicin, neomycin, silver sulfadiazine, mupirocin) through Omiderm, a synthetic wound covering, was tested in vitro and in 5 patients with full-thickness burns who had undergone tangential excision and split-thickness skin grafting. All antibiotic preparations tested penetrated both meshed and unmeshed Omiderm. Omiderm did not affect the zones of inhibition of antimicrobial activity as compared with controls.

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