Severe varicella caused by varicella-vaccine strain in a child with significant T-cell dysfunction.

Jean-Philippe, Patrick; Freedman, Abigail; Chang, Mary Wu; Steinberg, Sharon P; Gershon, Anne A; LaRussa, Philip S; Borkowsky, William · Pediatrics · 2007

case_report · Level V

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Abstract

In March 1995, the US Food and Drug Administration approved a live attenuated varicella vaccine for use in healthy children 12 months to 12 years old. We report here an 18-month-old girl with cell-mediated immunodeficiency who developed a severe vaccine-associated rash and clinical evidence of vaccine-associated pneumonia 1 month after inadvertent receipt of varicella vaccine.

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