Improving the prognosis of patients after radical cystectomy. Part II: the role of perioperative chemotherapy.
review · Level V
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Abstract
In this review we analyse the current status of perioperative systemic chemotherapy in the treatment of transitional cell carcinoma (TCC) of the bladder; instead of summarizing each neoadjuvant or adjuvant clinical trial we focus on the advantages and disadvantages of both strategies on the basis of theoretical considerations, and outline a rationale for a better design of future studies to confirm the efficacy of perioperative chemotherapy in TCC.
Medical subject headings
- Antineoplastic Combined Chemotherapy Protocols
- Carcinoma, Transitional Cell
- Cystectomy
- Urinary Bladder Neoplasms