alphaPlGF: a new kid on the antiangiogenesis block.
editorial · Level V
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Abstract
An agent that blocks tumor angiogenesis, growth, and metastasis without affecting normal tissues -- whether used alone or in combination with currently approved drugs -- would change the way we treat cancer. In this issue, Fischer et al. (2007) offer compelling evidence that a monoclonal antibody against placental growth factor (PlGF), a member of the VEGF family, has such potential in mice.
Medical subject headings
- Neovascularization, Pathologic
- Pregnancy Proteins