Is energy deficiency good in moderation?
editorial · Level V
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- Record sourced from PubMed, PMID 17981112.
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Abstract
In this issue, Pospisilik et al. (2007) demonstrate that a reduction in mitochondrial oxidative phosphorylation protects mice against obesity and diabetes. This finding suggests that the moderate deficiency in oxidative phosphorylation that is observed in peripheral tissues of insulin-resistant humans is not a causative factor in diabetes but may instead be a compensatory response.
Medical subject headings
- Oxidative Phosphorylation