The process of mRNA-tRNA translocation.

Frank, Joachim; Gao, Haixiao; Sengupta, Jayati; Gao, Ning; Taylor, Derek J · Proc Natl Acad Sci U S A · 2007

basic_science · Level V

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Abstract

In the elongation cycle of translation, translocation is the process that advances the mRNA-tRNA moiety on the ribosome, to allow the next codon to move into the decoding center. New results obtained by cryoelectron microscopy, interpreted in the light of x-ray structures and kinetic data, allow us to develop a model of the molecular events during translocation.

Medical subject headings