Antigen presentation the macrophage way.

Martinez-Pomares, Luisa; Gordon, Siamon · Cell · 2007

basic_science · Level V

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Abstract

Multiphoton intravital microscopy of lymph nodes has revolutionized the study of the early events leading to induction of acquired immunity. Using this technique, Junt et al. (2007) report in a recent issue of Nature that macrophages of the mouse lymph node subcapsular sinus facilitate B cell activation in vivo by collecting and displaying native antigen.

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