RNA Pol IV plays catch with Argonaute 4.
basic_science · Level V
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Abstract
Small-interfering RNAs regulate gene expression by affecting chromatin structure, transcription, translation, and RNA stability. In a recent report in Genes & Development, El-Shami et al. (2007) show that in plants, Argonaute 4-which is involved in RNA-directed DNA methylation-directly associates with RNA polymerase IVb through a repeat motif, establishing an intimate molecular link between RNAi and transcription.
Medical subject headings
- Arabidopsis Proteins
- DNA-Directed RNA Polymerases
- RNA Interference
- Transcription, Genetic