Microfluidic separation and capture of analytes for single-molecule spectroscopy.

Kim, Samuel; Huang, Bo; Zare, Richard N · Lab Chip · 2007

basic_science · Level V

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Abstract

A complex mixture of fluorescently labeled biological molecules is separated electrophoretically on a chip and the constituent molecules are confined in a sub-nanolitre microchamber, which allows analysis by various single-molecule techniques.

Medical subject headings