Coenzyme Q10 does not protect cochlear hair cells from death in the ischemic organotypic culture.
basic_science · Level V
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- Record sourced from PubMed, PMID 18036427.
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Abstract
To evaluate in vitro the effect of coenzyme Q10 (CoQ(10)) on ischemia-induced hair cell death. Organotypic cochlear cultures of newborn rats were subjected to ischemia with and without CoQ(10). Addition of CoQ(10) has not prevented HC loss. CoQ(10) seems to protect against only certain modes of cell death.
Medical subject headings
- Electron Transport Chain Complex Proteins
- Hair Cells, Auditory
- Ischemia
- Protective Agents
- Ubiquinone