FoxO3 controls dangerous proteolytic liaisons.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 18054311.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
FoxO3 regulates the transcription of critical components of the ubiquitin-proteasome system in muscle wasting. Two reports (Mammucari et al., 2007; Zhao et al., 2007) now implicate FoxO3 in the transcription of autophagy-related genes and provide the first direct evidence for a coordinated role of autophagy in muscle atrophy.
Medical subject headings
- Forkhead Transcription Factors
- Muscle, Skeletal
- Peptide Hydrolases