Does red-man reaction stimulate macrophage activation syndrome in children with systemic juvenile idiopathic arthritis?

Olgar, Seref; Ertugrul, Turkan; Devecioglu, Omer; Nisli, Kemal; Omeroglu, Rukiye Eker · J Rheumatol · 2007

case_report · Level V

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Abstract

Macrophage activation syndrome (MAS) is a major cause of death in patients with systemic juvenile idiopathic arthritis (JIA). We describe 4 patients who developed MAS during or after vancomycin treatment. Vancomycin should be used with great care in patients with systemic JIA.

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