A seminal finding for understanding HIV transmission.

Roan, Nadia R; Greene, Warner C · Cell · 2007

basic_science · Level V

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Abstract

Although the worldwide incidence of HIV infection is high, the retrovirus displays a surprisingly low infectivity in vitro. As a potential explanation for this discrepancy, Münch et al. (2007) now identify and characterize a factor found in human semen that under certain conditions can enhance HIV infectivity by more than 100,000-fold.

Medical subject headings