Dual role of the activated epidermal growth factor receptor in renal tubular cells during stress.
editorial · Level V
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Abstract
The paper by Sarro et al. raises the therapeutically important possibility that activation of the epidermal growth factor receptor (EGFR) after proximal tubule injury serves an unexpected death function and the EGFR-mediated survival signaling can be restored by identification of parallel and interacting pathways.
Medical subject headings
- ErbB Receptors
- Kidney Diseases
- Kidney Tubules, Proximal
- Oxidative Stress