Demonstration of a bio-microactuator powered by vascular smooth muscle cells coupled to polymer micropillars.

Tanaka, Yo; Sato, Kae; Shimizu, Tatsuya; Yamato, Masayuki; Okano, Teruo; Manabe, Ichiro; Nagai, Ryozo; Kitamori, Takehiko · Lab Chip · 2008

basic_science · Level V

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Abstract

We have demonstrated the working principle of a bio-microactuator using smooth muscle cells (SMCs) by driving micropillars coupled to cultured SMCs and controlled pillar displacements by chemical stimuli; the generated driving force was estimated to be over 1.1 microN.

Medical subject headings