Vitamin usage patterns in the prevention of advanced age-related macular degeneration.

Charkoudian, Leon D; Gower, Emily W; Solomon, Sharon D; Schachat, Andrew P; Bressler, Neil M; Bressler, Susan B · Ophthalmology · 2008

cross_sectional · Level IV

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Abstract

To describe micronutrient usage patterns among patients at a tertiary ophthalmic center. Cross-sectional clinical case series. Three hundred thirty-two adult patients with a diagnosis of age-related macular degeneration (AMD). Participants were surveyed about micronutrient usage patterns. The treating ophthalmologist recorded AMD severity using the Age-Related Eye Disease Study (AREDS) classification system. Responses to study questionnaire and level of AMD severity. Among 332 participants, 309 (93%) were using supplements, among which 174 (52%) supplemented with an AREDS-like formulation. Of these 174, 140 (80%) were considered AREDS supplement candidates based on study guidelines. Applying AREDS supplementation guidelines to the full cohort, 228 (69%) were candidates for supplementation. Only 140 (61%) of these individuals were confirmed to be using the correct formulation and dosage; an additional 13 (6%) used the AREDS formulation but were not using the recommended dosage. Among patients receiving care for AMD at a tertiary retinal center, more than one third of those deemed candidates for AREDS-type supplements were not using them or were using an incorrect dose. Furthermore, nearly one fifth of participants who were using high-dose supplements did not have a level of AMD anticipated to benefit from usage. Increased patient education is needed regarding the recommendations of AREDS.

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