Tight regulation of the Epstein-Barr virus setpoint: interindividual differences in Epstein-Barr virus DNA load are conserved after HIV infection.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 18171268.
- Also identified by DOI 10.1086/524079.
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Abstract
Healthy individuals carry a constant number of Epstein-Barr virus-infected B cells in the peripheral blood over time. Here, we show that interindividual differences in Epstein-Barr virus DNA levels are maintained after HIV infection, providing evidence for the existence of an individual Epstein-Barr virus setpoint. Immune activation may contribute to the increase in this setpoint after human immunodeficiency virus seroconversion.
Medical subject headings
- DNA, Viral
- Epstein-Barr Virus Infections
- HIV
- HIV Infections
- Herpesvirus 4, Human