No association between histo-blood group antigens and susceptibility to clinical infections with genogroup II norovirus.

Halperin, Tamar; Vennema, Harry; Koopmans, Marion; Kahila Bar-Gal, Gila; Kayouf, Raid; Sela, Tamar; Ambar, Ruhama; Klement, Eyal · J Infect Dis · 2008

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Abstract

Noroviruses (NoVs) are a leading cause of viral gastroenteritis in humans. In the present study, the association between NoV susceptibility and the ABO histo-blood group was studied during 2 outbreaks of acute gastroenteritis in military units in Israel caused by genogroup II (GII) NoVs. The findings demonstrate that, unlike for genogroup I of NoV, there is no association between the ABO histo-blood group and clinical infection with GII NoVs. This is the largest study to test the association between NoVs, proven clinical infection with GII, and the ABO histo-blood group.

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