Circulating fibrocytes: cellular basis for NSF.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 18180007.
- Also identified by DOI 10.1016/j.jacr.2007.08.016.
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Abstract
Since the discovery of the circulating fibrocyte as a collagen-producing cell of the peripheral blood, the physiologic and pathologic role of this unique cell population has grown steadily. The present review summarizes the known biology of fibrocytes and discusses evidence for their role in the pathogenesis of nephrogenic systemic fibrosis. Possible mechanisms by which gadolinium may influence the activation or trafficking properties of fibrocytes leading to tissue fibrosis are discussed.
Medical subject headings
- Connective Tissue
- Contrast Media
- Fibroblasts
- Gadolinium
- Skin Diseases