Diagnosis and management of HIV drug hypersensitivity.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 18190954.
- Also identified by DOI 10.1016/j.jaci.2007.10.021.
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Abstract
Drug hypersensitivity reactions are an important cause of morbidity in HIV-infected patients who take complex medication regimens. Correct diagnosis and management of these reactions are essential in the clinical care of HIV disease. Trimethoprim-sulfamethoxazole, abacavir, nevirapine, atazanavir, and enfuvirtide can all cause hypersensitivity rashes. In this review, we discuss the evidence for immunologic mechanisms of hypersensitivity reactions to HIV medications, the clinical characteristics of these reactions, and guidelines that currently exist for their identification and management.
Medical subject headings
- Anti-HIV Agents
- Drug Hypersensitivity
- Exanthema
- HIV Infections
- Immunosuppressive Agents