XMAP215: a tip tracker that really moves.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18191214.
- Also identified by DOI 10.1016/j.cell.2007.12.019 and PMC identifier 2812705.
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Abstract
XMAP215 is a microtubule plus-end binding protein implicated in modulating microtubule dynamics. In this issue, Brouhard et al. (2008) propose a new mechanism to explain how XMAP215 promotes microtubule growth. They report that XMAP215 moves with the growing microtubule plus ends where it catalyzes the addition of tubulin subunits.
Medical subject headings
- Microtubule-Associated Proteins
- Microtubules
- Tubulin
- Xenopus Proteins