PTRF triggers a cave in.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18191216.
- Also identified by DOI 10.1016/j.cell.2007.12.021.
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Abstract
Caveolae are small membrane invaginations important for cell signaling that are characterized by the presence of caveolin proteins. Hill et al. (2008) have now identified PTRF as a new constituent of the caveolar coat. In the absence of PTRF, caveolae flatten and caveolin-1 is released into the cell membrane, where it is rapidly internalized and degraded.
Medical subject headings
- Caveolae
- Cell Membrane
- RNA-Binding Proteins