The role of heparan sulfate in the glomerular basement membrane.

Morita, H; Yoshimura, A; Kimata, K · Kidney Int · 2008

editorial · Level V

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Abstract

Recent studies, including those by van den Hoven and colleagues, have challenged the classic negative-charge theory of glomerular filtration. However, the possibility remains that heparan sulfate in the glomerular basement membrane plays a role in maintaining the glomerular filtration barrier.

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