Enhanced Fe ion-uptake activity in Helicobacter pylori strains isolated from patients with iron-deficiency anemia.

Yokota, Shin-ichi; Konno, Mutsuko; Mino, Emi; Sato, Kohei; Takahashi, Michiko; Fujii, Nobuhiro · Clin Infect Dis · 2008

basic_science · Level V

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Abstract

Recent studies have suggested a link between iron-deficiency anemia and Helicobacter pylori infection. In the current study, strains of H. pylori derived from patients with iron-deficiency anemia showed enhanced Fe ion uptake and Fe ion-dependent rapid growth compared with those from patients with non-iron-deficiency anemia. H. pylori with enhanced Fe ion-uptake ability may be a causative factor for iron-deficiency anemia.

Medical subject headings