Psychiatric comorbidity in young cocaine users: induced versus independent disorders.

Herrero, M Jesús; Domingo-Salvany, Antonia; Torrens, Marta; Brugal, M Teresa; ITINERE Investigators · Addiction · 2008

cross_sectional · Level IV

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Abstract

To examine the psychiatric status of young cocaine users using a validated instrument for the evaluation of psychiatric comorbidity, emphasizing the distinction between independent and induced psychiatric conditions. Cross-sectional study. Barcelona, Spain. A cohort of 139 young (18-30 years) adult current regular cocaine users. The Psychiatric Research Interview for Substance and Mental Disorders (PRISM-IV, which produces diagnoses according to DSM-IV criteria, including Axis II antisocial and borderline personality disorders). Nearly 42.5% of the subjects presented psychiatric comorbidity. The most common Axis I diagnoses were mood disorders (26.6%) and anxiety disorders (13%). Increasing age, having ever received treatment for drug use and freebase cocaine use were associated with substance-induced disorders diagnoses relative to primary Axis I disorders. This study has shown a relatively high prevalence of psychiatric comorbidity in cocaine users recruited in non-clinical settings. Future studies examining potential differential factors associated with primary versus substance-induced disorders are necessary to optimize the implementation of more suitable approaching programmes for young regular cocaine users.

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