Mammalian cells change volume during mitosis.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18213385.
- Also identified by DOI 10.1371/journal.pone.0001477 and PMC identifier PMC2278564.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Using single cell-imaging methods we have found that the volume of adherent cells grown in culture decreases as the cells rounds when it enters mitosis. A minimal volume is reached at metaphase. Rapid volume recovery initiates before abscission as cells make the transition from metaphase to cytokinesis. These volume changes are simultaneous with the rapid surface area decrease and recovery observed in mitotic cells [1].