Chimerism and tolerance in a recipient of a deceased-donor liver transplant.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 18216357.
- Also identified by DOI 10.1056/NEJMoa0707255.
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Abstract
Complete hematopoietic chimerism and tolerance of a liver allograft from a deceased male donor developed in a 9-year-old girl, with no evidence of graft-versus-host disease 17 months after transplantation. The tolerance was preceded by a period of severe hemolysis, reflecting partial chimerism that was refractory to standard therapies. The hemolysis resolved after the gradual withdrawal of all immunosuppressive therapy.
Medical subject headings
- Hemolysis
- Liver Transplantation
- Transplantation Chimera
- Transplantation Tolerance