On distance and similarity in fold space.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18227113.
- Also identified by DOI 10.1093/bioinformatics/btn040.
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Abstract
Metric information on similarities and distances in fold space is essential for quantitative work in structural bioinformatics and structural biology. Here we derive a suitable metric for protein structures from the fundamental axioms of similarity. Derivation of the metric also clarifies the relationship between the interrelated concepts of distance and similarity.
Medical subject headings
- Models, Chemical
- Models, Molecular
- Proteins
- Sequence Alignment
- Sequence Analysis, Protein
- Software