Case-control study on occupational risk factors for soft-tissue sarcoma.

Abstract

The main objective of this study was to investigate potential association between development of soft-tissue sarcoma (STS) and occupational exposures related to farming and the agricultural industry in Canada. A population-based case-control study of STS was conducted among Canadian men stratified by province of residence and age group. Conditional logistic regression was used to fit multivariable statistical models. The following variables were positively associated with the incidence of STS: machinist, chicken farming, pulp and paper industry worker, and apartment complex worker. Mixed farming and exposure to chlorine were negatively associated with STS. The higher risk of developing STS may be associated with longest-held job as a machinist, short-term jobs as chicken farm worker, pulp and paper industry worker, and apartment complex worker.