The single nerve fiber action potential and the filter bank--a modeling approach.

Abstract

Single fiber action potentials (SFAPs) from peripheral nerves, such as recorded with cuff electrodes, can be modelled as the convolution of a source current and a weight function that describes the recording electrodes and the surrounding medium. It is shown that for cuff electrodes, the weight function is linearly scaled with the action potential (AP) velocity and that it is, therefore, possible to implement a model of the recorded SFAPs based on a wavelet multiresolution technique (filterbank), where the wavelet scale is proportional to the AP velocity. The model resulted in single fiber action potentials matching the results from other models with a goodness of fit exceeding 0.99. This formulation of the SFAP may serve as a basis for model-based wavelet analysis and for advanced cuff design.