Targeting PDGF signaling in carcinoma-associated fibroblasts controls cervical cancer in mouse model.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18232729.
- Also identified by DOI 10.1371/journal.pmed.0050024 and PMC identifier 2214795.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
The authors discuss a new study of a paracrine regulatory circuit centered on PDGF receptor signaling in cancer-associated fibroblasts and pericytes of a mouse model of cervical carcinoma.
Medical subject headings
- Antineoplastic Agents
- Carcinoma
- Neoplasm Proteins
- Piperazines
- Platelet-Derived Growth Factor
- Protein Kinase Inhibitors
- Pyrimidines
- Receptors, Platelet-Derived Growth Factor
- Uterine Cervical Neoplasms