Unraveling the role of connective tissue growth factor in diabetic nephropathy.

Schmidt-Ott, K M · Kidney Int · 2008

editorial · Level V

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Abstract

Marked upregulation of the secreted extracellular matrix-associated protein connective tissue growth factor (CTGF) in the glomerulus coincides with the onset of diabetic nephropathy. Recent studies, including the one by Yokoi et al., shed light on the role of CTGF in glomerular injury.

Medical subject headings