Facultative endocrine progenitor cells in the adult pancreas.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18243094.
- Also identified by DOI 10.1016/j.cell.2008.01.004.
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Abstract
Using a unique injury model of the pancreas in mouse, Xu et al. (2008) now reveal the involvement of neurogenin3, a marker for embryonic-type endocrine progenitor cells, in the formation of new insulin-producing beta cells. These neurogenin3-positive facultative endocrine progenitor cells in the adult pancreas may be of potential value for treating diabetes.
Medical subject headings
- Basic Helix-Loop-Helix Proteins
- Insulin-Secreting Cells
- Nerve Tissue Proteins
- Pancreas
- Stem Cells