Fighting fat with muscle: bulking up to slim down.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 18249167.
- Also identified by DOI 10.1016/j.cmet.2008.01.003.
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Abstract
Akt1 is a well-characterized mediator of muscle hypertrophy. In this issue of Cell Metabolism, Izumiya et al. (2008) reveal a striking link between Akt1 signaling, fast muscle fiber size, and whole-body metabolism. These results provide new insights into the ability of muscle to combat diet-induced obesity and metabolic dysfunction.
Medical subject headings
- Adipose Tissue
- Muscle, Skeletal
- Proto-Oncogene Proteins c-akt
- Weight Loss