A kit formulation for preparation of iodine-123-IBZM: a new CNS D-2 dopamine receptor imaging agent.
basic_science · Level V
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Abstract
A method for the preparation of iodine-123IBZM, a central nervous system D-2 imaging agent, is reported. By using a rapid filtration technique to remove the unreacted iodide, the preparation can be completed in less than 20 min (overall yield greater than 60%). The product, with high purity (greater than or equal to 95%) and specific activity, is suitable for human use.
Medical subject headings
- Benzamides
- Brain
- Pyrrolidines
- Reagent Kits, Diagnostic
- Receptors, Dopamine