A preliminary study comparing the endometrial expression of inhibin, activin and follistatin in women with a history of implantation failure after IVF treatment and a control group.
case_control · Level III
Where this comes from
- Record sourced from PubMed, PMID 18271891.
- Also identified by DOI 10.1111/j.1471-0528.2007.01624.x.
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Abstract
The aim of this study was to evaluate the expression of activin: beta A and beta B subunit and follistatin in endometrium of women with implantation failure (n = 10) and compare it with a fertile control group (n = 7). Immunohistochemical staining intensity for follistatin in the endometrial glandular epithelium from women with implantation failure were significantly lower than that in control women (P = 0.03). The decreased expression of follistatin in epithelial cells in the endometrium of women with implantation failure after in vitro fertilisation (IVF) may suggest that follistatin may play a role in the implantation process.
Medical subject headings
- Embryo Implantation
- Endometrium
- Follistatin
- Infertility, Female
- Inhibin-beta Subunits