Autophagy as an important process in gut homeostasis and Crohn's disease pathogenesis.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 18272545.
- Also identified by DOI 10.1136/gut.2007.134254 and PMC identifier 2735854.
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Abstract
Recent genome-wide association studies in Crohn’s Disease have identified genetic variation within two genes involved in a biological process known as autophagy. These genetic findings reveal an important role for autophagic processes in both gut homeostasis and in the development of chronic inflammation of the gastrointestinal tract.
Medical subject headings
- Autophagy
- Crohn Disease
- Gastrointestinal Tract
- Homeostasis