Composite hemangioendothelioma of the oral cavity: case report and review of the literature.

Fasolis, Massimo; Iaquinta, Caterina; Montesco, Maria Cristina; Garzino-Demo, Paolo; Tosco, Paolo; Tanteri, Giulia; Bonandini, Elena; Ninfo, Vito et al. · Head Neck · 2008

case_report · Level V

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Abstract

Composite hemangioendothelioma is a rare histopathologic feature, which is part of the hemangioendothelioma family. This is a heterogeneous group of vascular neoplasia with a high tendency to local relapse but a rare predisposition to metastatic spread. Composite hemangioendothelioma mainly affects adults and is usually localized in the distal extremity of the limbs. To date, only 1 case has been detected in the oral cavity. A case of composite hemangioendothelioma in a 38-year-old man is reported. The lesion was localized in the left cheek vestibular mucosa. It was surgically excised with a 1-cm safety margin. Reconstruction was performed with a platysma myocutaneous flap. At present, the patient is free from recurrence. The aesthetic and functional outcomes are satisfactory. This case demonstrates how a composite hemangioendothelioma histological diagnosis can be difficult to achieve. Furthermore, therapy must be surgical and excision should be wide.

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