The effect of thoracic epidural bupivacaine and an intravenous adrenaline infusion on gastric tube blood flow during esophagectomy.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 18292435.
- Also identified by DOI 10.1213/ane.0b013e318164f153.
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Abstract
Gastric tube necrosis is a major cause of anastomotic leak after esophagectomy. A correlation has been shown between reduced flux at the anastomotic end of the gastric tube and anastomotic leaks. We prospectively studied the effect of intraoperative thoracic epidural bupivacaine and subsequent adrenaline infusion on hemodynamics and flux in the gastric tube. Administering the epidural bolus significantly decreased flux at the anastomotic end of the gastric tube (P < 0.01). Gastric flux was returned to baseline by an adrenaline infusion. The administration of a thoracic epidural bolus may decrease flux at the anastomotic end of the gastric tube.
Medical subject headings
- Analgesia, Epidural
- Anesthetics, Local
- Bupivacaine
- Epinephrine
- Esophagectomy
- Stomach
- Surgically-Created Structures
- Vasoconstrictor Agents