The effect of vaginal douching cessation on bacterial vaginosis: a pilot study.

Brotman, Rebecca M; Ghanem, Khalil G; Klebanoff, Mark A; Taha, Taha E; Scharfstein, Daniel O; Zenilman, Jonathan M · Am J Obstet Gynecol · 2008

prospective_cohort · Level II

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Abstract

The objective of the study was to evaluate the risk for bacterial vaginosis (BV) in a douching cessation trial. Thirty-nine reproductive-age women who reported use of douche products were enrolled into a 20-week study consisting of a 4 week douching observation (phase I) followed by 12-weeks of douching cessation (phase II). In phase III, participants then chose to resume douching or continue cessation for the remaining 4 weeks. Self-collected vaginal samples were obtained twice weekly in the first 16 weeks, and 1 sample was collected during week 20 (1107 samples total). BV was diagnosed by Nugent score of 7 or greater. Conditional logistic regression was used to evaluate douching cessation on the risk of BV. The adjusted odds ratio (aOR) for BV in the douching cessation phase, as compared with the douching-observation phase was 0.76 (95% confidence interval [CI], 0.33 to 1.76). Among women who reported their primary reason for douching was to cleanse after menstruation, BV was significantly reduced in douching cessation (aOR:0.23; 95% CI, 0.12 to 0.44). Vaginal douching cessation may reduce the risk for BV in a subset of women.

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