FTFD: an informatics pipeline supporting phylogenomic analysis of fungal transcription factors.
basic_science · Level V
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- Record sourced from PubMed, PMID 18304934.
- Also identified by DOI 10.1093/bioinformatics/btn058.
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Abstract
Genomes of more than 60 fungal species have been sequenced to date, yet there has been no systematic approach to analyze fungal transcription factors (TFs) kingdom widely. We developed a standardized pipeline for annotating TFs in fungal genomes. Resulting data have been archived in a new database termed the Fungal Transcription Factor Database (FTFD). In FTFD, 31,832 putative fungal TFs, identified from 62 fungal and 3 Oomycete species, were classified into 61 families and phylogenetically analyzed. The FTFD will serve as a community resource supporting comparative analyses of the distribution and domain structure of TFs within and across species. All data described in this study can be browsed through the FTFD web site at http://ftfd.snu.ac.kr/.
Medical subject headings
- Chromosome Mapping
- Database Management Systems
- Databases, Protein
- Evolution, Molecular
- Fungal Proteins
- Multigene Family
- Transcription Factors