PPAR gamma: ally and foe in bone metabolism.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 18316021.
- Also identified by DOI 10.1016/j.cmet.2008.02.005.
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Abstract
Bone homeostasis is a well-balanced process that is largely dependent on the contribution of both bone-forming osteoblasts and bone-resorbing osteoclasts. A new study (Wan et al., 2007) suggests a previously unsuspected role for the transcription factor PPARgamma in promoting bone progenitors to the osteoclastic lineage.
Medical subject headings
- Bone Remodeling
- Osteoblasts
- Osteoclasts
- PPAR gamma
- Signal Transduction