Ghrelin gets its GOAT.
Where this comes from
- Record sourced from PubMed, PMID 18316023.
- Also identified by DOI 10.1016/j.cmet.2008.02.009.
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Abstract
Ghrelin, a powerful appetite-stimulating hormone secreted by the stomach, is modified by an octanyl side chain on its third amino acid, a serine, which is essential for its activity. A recent study (Yang et al., 2008) reports identification of the enzyme catalyzing the addition of this octanyl, GOAT.
Medical subject headings
- Acyltransferases
- Appetite Regulation
- Ghrelin