Glomerulotubular balance, tubuloglomerular feedback, and salt homeostasis.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 18322161.
- Also identified by DOI 10.1681/ASN.2007121326.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The homeostasis of NaCl is critical to complex organisms with closed blood systems. Kidneys regulate this salt excretion by modulating the rapport between glomeruli and tubules. The tubules respond to glomeruli with glomerulotubular balance, whereas glomeruli respond to tubules through tubuloglomerular feedback. These relationships are dynamic, mysterious, and amenable to mathematical analyses. The biology underlining what is known about these interactions is observational, fragmentary, and somewhat inconclusive. Discussed here is a simple tethering of these interrelated concepts.
Medical subject headings
- Kidney Glomerulus
- Kidney Tubules
- Sodium Chloride