Ketoconazole-induced fulminant hepatitis necessitating liver transplantation.

Knight, T E; Shikuma, C Y; Knight, J · J Am Acad Dermatol · 1991

case_report · Level V

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Abstract

The most serious side effect of ketoconazole is hepatitis, which has proved fatal in seven reported cases. We present a case of fulminant hepatic failure in a 45-year-old Oriental woman that probably would have been fatal except for a successful liver transplant. A review of the literature of fatalities associated with ketoconazole is presented.

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