Diabetes and cancer in veterans of Operation Ranch Hand after adjustment for calendar period, days of spraying, and time spent in Southeast Asia.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 18332783.
- Also identified by DOI 10.1097/JOM.0b013e31815f889b.
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Abstract
The Air Force Health Study was launched in 1980 as part of a Federal effort to resolve the Agent Orange issue. To study diabetes and cancer with additional adjustment for days of spraying, calendar period of service, and time spent in Southeast Asia (SEA). This was a longitudinal study of veterans of Operation Ranch Hand, the unit responsible for spraying Agent Orange and other 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-contaminated herbicides in Vietnam from 1962 to 1971. Associations between TCDD and diabetes and between TCDD and cancer in Ranch Hand veterans are strengthened after adjustment for calendar period of service, days of spraying, and, for cancer, time spent in SEA. Calendar period of service, days of spraying, and time spent in SEA are important confounders in the Air Force Health Study.
Medical subject headings
- 2,4,5-Trichlorophenoxyacetic Acid
- 2,4,5-Trichlorophenoxyacetic Acid/adverse effects
- 2,4,5-Trichlorophenoxyacetic Acid/blood
- 2,4-Dichlorophenoxyacetic Acid
- 2,4-Dichlorophenoxyacetic Acid/adverse effects
- 2,4-Dichlorophenoxyacetic Acid/blood
- Aged
- Agent Orange
- Asia, Southeastern
- Confounding Factors, Epidemiologic
- Defoliants, Chemical
- Defoliants, Chemical/adverse effects
- Defoliants, Chemical/blood
- Diabetes Mellitus
- Diabetes Mellitus/blood
- Diabetes Mellitus/chemically induced
- Diabetes Mellitus/epidemiology
- Environmental Pollutants
- Environmental Pollutants/adverse effects
- Environmental Pollutants/blood
- Humans
- Longitudinal Studies
- Middle Aged
- Neoplasms
- Neoplasms/blood
- Neoplasms/chemically induced
- Neoplasms/epidemiology
- Occupational Exposure
- Occupational Exposure/adverse effects
- Occupational Exposure/analysis
- Polychlorinated Dibenzodioxins
- Polychlorinated Dibenzodioxins/adverse effects
- Polychlorinated Dibenzodioxins/blood
- Proportional Hazards Models
- Risk Factors
- SEER Program
- Time Factors
- United States
- United States/epidemiology
- Veterans
- Veterans/statistics & numerical data
- Vietnam Conflict