PET imaging with 11C-acetate in prostate cancer: a biochemical, radiochemical and clinical perspective.

Soloviev, Dmitri; Fini, Alberto; Chierichetti, Franca; Al-Nahhas, Adil; Rubello, Domenico · Eur J Nucl Med Mol Imaging · 2008

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Abstract

In the present study, the potential clinical role of 11C-acetate PET mainly in the differential diagnosis, in the staging and in the follow-up of prostate cancer patients is reported. Each of the above points has been accurately investigated by studying the specific biochemical and radiobiochemical behaviour of this positron emitter compound. The imaging quality of 11C-acetate PET and its unique mechanisms of cellular uptake, make such radiotracer a powerful tool in evaluating all the steps of the prostatic cancer.

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